Publications

2016 Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) β Agonist Journal of Medicinal Chemistry
2016 Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core Bioorganic & Medicinal Chemistry Letters
2016 Identification of Spirooxindole and Dibenzoxazepine Motifs as Potent Mineralocorticoid Receptor Antagonists Bioorganic & Medicinal Chemistry Letters
2011 A Strategy for Antagonizing Quorum Sensing Molecular Cell
2007 Structural Basis for Antiactivation in Bacterial Quorum Sensing PNAS
2007 Biochemical Characterization of a Regulatory Cascade Controlling Transcription of the Pseudomonas Aeruginosa Type III Secretion System JBC
2006 Crystal Structure and Mechanism of TraM2, a Second Quorum-Sensing Antiactivator of Agrobacterium Tumefaciens Strain A6 Journal of Bacteriology
2006 Characterization of ExsC and ExsD Self-Association and Complex Formation Journal of Bacteriology
2006 Dual Control of Quorum Sensing by Two TraM-Type Antiactivators in Agrobacterium tumefaciens Octopine Strain A6 Journal of Bacteriology
2004 Quorum-Sensing Anti-Activator TraM Forms a Dimer that Dissociates to Inhibit TraR Molecular Microbiology